An example of a bone marrow disease is aplastic anemia, which occurs when the bone marrow is not creating any blood cells. For example, infections caused by the Streptococci and Meningococci bacteria can lead to the rupturing of the RBC because of the toxins that these microorganisms produce.īecause the bone marrow is the creator of RBCs, a disease or damage within this organ can lead to low levels of Hgb and HCT. The premature destruction of RBCs can also occur in other diseases that are unrelated to the blood.
In other types of anemia such as sickle cell and spherocytosis, the body attacks and destroys the RBCs with abnormal shapes. One example is hemolytic anemia, wherein there is a premature destruction of RBCs, and the bone marrow is unable to produce enough blood cells. Various medical conditions can disrupt this normal process leading to low Hgb and low HCT. Then, the destruction of these blood cells occurs in the spleen and the bone marrow will release new RBCs.
Normally, RBCs can stay in the bloodstream for about 120 days. Premature Destruction of Red Blood Cells.When a patient has a low Hgb and HCT with no visible signs of bleeding, the doctor will order a stool examination to test for the presence of blood. For severe blood loss in the gastrointestinal tract, the common causes are cancer or ulcer of the stomach, intestine, and esophagus. Most types of anemia are due to bleeding in the digestive tract. A major problem occurs during internal bleeding because the blood loss can go on undetected for a long period. Most of the time, blood loss is a manageable condition as long as it is visible like in cases of injuries and heavy menstrual bleeding. The most common cause of low Hgb and low HCT is bleeding, which can be either visible or hidden. Various medical conditions can cause low HCT and Hgb, which includes the following: The table below contains the normal HCT and Hgb values. The normal levels for hematocrit and hemoglobin will vary depending on your age and gender. Normal Level of Hematocrit (HCT) and Hemoglobin (HGB) For this reason, it is valuable to learn and understand the possible reasons why a person experiences a decrease in Hgb and HCT levels. If the level is very low, it can be a life-threatening condition. A low Hgb and HCT will mean that there is insufficient oxygen circulating throughout the body. It is vital that one must keep their HCT and Hgb levels within the normal range. The Hgb levels, on the other hand, will indicate the amount of hemoglobin in the blood. The HCT levels will reveal the percentage of RBCs in a certain amount of blood. The hemoglobin (Hgb) and hematocrit (HCT) levels will help determine a person’s total red blood cell count. For this reason, it is vital to have the normal amount of RBCs. With the help of hemoglobin, the RBC is able to carry oxygen and nutrients all over the body. It’s important to be aware of the symptoms of a B-12 deficiency.The bone marrow creates red blood cells (RBCs), which contains hemoglobin. These types of anemia can develop if your diet is low in B vitamins or if your body does not absorb B-12 or folate properly. Both of these vitamins are required by your body in order to make red blood cells. High MCH value can often be caused by anemia due to a deficiency of B vitamins, particularly B-12 and folate.
This means that there is a larger amount of hemoglobin present per red blood cell.
An MCH value calculated above 33.2 pg is considered high MCH.
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